TNIP1 (NM_006058) Human Untagged Clone

CAT#: SC116383

TNIP1 (untagged)-Human TNFAIP3 interacting protein 1 (TNIP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TNIP1
• Synonyms: ABIN-1; NAF1; nip40-1; VAN
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116383 sequence for NM_006058 edited (data generated by NextGen Sequencing)
  ATGGAAGGGAGAGGACCGTACCGGATCTACGACCCTGGGGNCAGCGTGCCCTCAGGNGAG
  GCATCCGCAGCTTTTGAGCGCCTAGTGAAGGAGAATTCCCGGCTGAAGGAAAAAATGCAA
  GGGATAAAGATGTTAGGGGAGCTTTTGGAAGAGTCCCAGATGGAAGCGACCAGGCTCCGG
  CAGAAGGCAGAGGAGCTAGTGAAGGACAACGAGCTGCTCCCACCACCTTCTCCCTCCTTG
  GGCTCCTTCGACCCCCTGGCTGAGCTCACAGGAAAGGACTCAAATGTCACAGCATCTCCC
  ACAGCCCCTGCATGCCCCAGTGACAAGCCAGCACCAGTCCAGAAGCCTCCATCCAGTGGC
  ACCTCCTCTGAATTTGAAGTGGTCACTCCTGAGGAGCAGAATTCACCAGAGAGCAGCAGC
  CATGCCAATGCGATGGCGCTGGGCCCCCTGCCCCGTGAGGACGGCAACCTGATGCTGCAC
  CTGCAGCGCCTGGAGACCACGCTGAGTGTGTGTGCCGAGGAGCCGGACCACGGCCAGCTC
  TTCACCCACCTGGGCCGCATGGCCCTGGAGTTCAACCGACTGGCATCCAAGGTGCACAAG
  AATGAGCAGCGCACCTCCATTCTGCAGACCCTGTGTGAGCAGCTTCGGAAGGAGAACGAG
  GCTCTGAAGGCCAAGTTGGATAAGGGCCTGGAACAGCGGGATCAGGCTGCCGAGAGGCTG
  CGGGAGGAAAATTTGGAGCTCAAGAAGTTGTTGATGAGCAATGGCAACAAAGAGGGTGCG
  TCTGGGCGGCCAGGCTCACCGAAGATGGAAGGGACAGGCAAGAAGGCAGTGGCTGGACAG
  CAGCAGGCTAGTGTGACGGCAGGTAAGGTCCCAGAGGTGGTGGCCTTGGGCGCAGCCGAG
  AAGAAGGTGAAGATGCTGGAGCAGCAGCGCAGTGAGCTGCTGGAAGTGAACAAGCAGTGG
  GACCAGCATTTCCGGTCCATGAAGCAGCAGTATGAGCAGAAGATCACTGAGCTGCGTCAG
  AAGCTGGCTGATTTGCAGAAGCAGGTGACTGACCTGGAGGCCGAGCGGGAGCAGAAGCAG
  CGTGACTTTGACCGCAAGCTCCTCCTGGCCAAGTCCAAGATTGAAATGGAGGAGACCGAC
  AAGGAGCAGCTGACAGCAGAGGCCAAGGAGCTGCGCCAAAAGGTCAAGTACCTGCAGGAT
  CAGCTGAGCCCACTCACCCGACAGCGTGAGTACCAGGAAAAGGAGATCCAGCGGCTCAAC
  AAGGCCCTGGAGGAAGCACTGAGCATCCAAACCCCGCCATCATCTCCACCAACAGCATTT
  GGGAGCCCAGAAGGAGCAGGGGCCCTCCTAAGGAAACAGGAGCTGGTCACGCAGAATGAG
  TTGCTGAAACAGCAGGTGAAGATCTTCGAGGAGGACTTCCAGAGGGAGCGCAGTGATCGT
  GAGCGCATGAATGAGGAGAAGGAAGAGCTGAAGAAGCAAGTGGAGAAGCTGCAGGCCCAG
  GTCACCCTGTCAAATGCCCAGCTAAAAGCATTCAAAGATGAGGAGAAGGCAAGAGAAGCC
  CTCAGACAGCAGAAGAGGAAAGCAAAGGCCTCAGGAGAGCGTTACCATGTGGAGCCCCAC
  CCAGAACATCTCTGCGGGGCCTACCCCTACGCCTACCCGCCCATGCCAGCCATGGTGCCA
  CACCATGGCTTCGAGGACTGGTCCCAGATCCGCTACCCCCCTCCCCCCATGGCCATGGAG
  CACCCGCCCCCACTCCCCAACTCGCGCCTCTTCCATCTGCCGGAATACACCTGGCGTCTA
  CCCTGTGGAGGGGTTCGAAATCCAAATCAGAGCTCCCAAGTGATGGACCCTCCCACAGCC
  AGGCCTACAGAACCAGAGTCTCCAAAAAATGACCGTGAGGGGCCTCAGTGA
  
  Clone variation with respect to NM_006058.3
  41 g=>n;57 a=>n
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006058 unedited
  GTTAGNATTTTGTAATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGCGGGGC
  TGGACGCAGCAAGCGGGGCGCTGTGTCCCCAAGCTCCCCGTCCTCGGCCAGGCGGGCACC
  ACGGCAGGGGCTGAGCTACCCTCATGGAAGGGAGAGGACCGTACCGGATCTACGACCCTG
  GGGGCAGCGTGCCCTCAGGAGAGGCATCCGCAGCTTTTGAGCGCCTAGTGAAGGAGAATT
  CCCGGCTGAAGGAAAAAATGCAAGGGATAAAGATGTTAGGGGAGCTTTTGGAAGAGTCCC
  AGATGGAAGCGACCAGGCTCCGGCAGAAGGCAGAGGAGCTAGTGAAGGACAACGAGCTGC
  TCCCACCACCTTCTCCCTCCTTGGGCTCCTTCGACCCCCTGGCTGAGCTCACAGGAAAGG
  ACTCAAATGTCACAGCATCTCCCACAGCCCCTGCATGCCCCAGTGACAAGCCAGCACCAG
  TCCAGAAGCCTCCATCCAGTGGCACCTCCTCTGAATTTGAAGTGGTCACTCCTGAGGAGC
  AGAATTCACCAGAGAGCAGCAGCCATGCCAATGCGATGGCGCTGGGCCCCCTGCCCCGTG
  AGGACGGCAACCTGATGCTGCACCTGCAGCGCCTGGAGACCACGCTGAGTGTGTGTGCCG
  AGGAGCCGGACCACGGCCAGCTCTTCACCCACCTGGGCCGCATGGCCCTGGAGTTCAACC
  GACTGGCATCCAAGGTGCACAAGAATGAGCAGCGCACCTCCATTCTGCAGACCCTGTGTG
  AGCAGCTTCGGAAGGAGAACGAGGCTCTGAAGGCCAAGTGGNATAAGGGCCTGGAACAGC
  GGATCAGGCTGCCGAGAGGCTGCGGGAGGGAAAATTGGAGCTCAAGAAGTNGNTGATGAG
  CATGGCACAAAAAGGGTGCGTCTGGGCGGCCAGGCTCACCGAAAATGGAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006058 unedited
  GCCGCAATCNANAGTCGAGTTTTTTTTTTTTTTTTTTGATCTTCTTCAACTTGGATTTAT
  GTCCATGATTCGTGCAAATAGCTATCCAGGGATGGACAGCCACCCTAATCTGGGCTTCTG
  GCACCACAGGCCTCCAGCTATGGGGTCCAGGGTCTGAACCTCAGGGCCTGGCAGCTTCAG
  GCTGGCGCCCCTCGGCGGACGTGGCTGGCATGGCCTTCTCCCATCTGTGATGGCTTCAGC
  AAGGCTACTGTGAGTGGTGGTGGAGAGGGCCCCAAAGCCAGAATATCCATCATTCTCTTC
  TGTTCTGGAGACAAACCCACACTTCCCACAGCTCCTCACAGAGGGGTAGGGGTGTGCGTG
  GGGCANGTCCTGCTACAGAGCTTGAAGCAAAAATTAAACACACACACAAATTGGTCATGG
  CAACTAGAGGGCCTGAAACCACTTCCGGGAGGTTTTGAAGGAAGGGGGTCTTGGCTGCCT
  CCCACTCTTAGGATTGCTGCTCCTGGAGGCTTCTGCAACGGATGGTGGGTCAAAGCCGGA
  TGAGGCCTCTCTCCACTCAGCAGCAGGGAAAGAGTTTTTCCCAGTCACTCCCAGCAGAGT
  ACAAATGAAAGCCTTCTGGGTGGAGCCTCCCCAGTCCTGTAAACAGCTCACTTCACGGCA
  CCGGTGTACAAGCTTGGCACCCATCTCAGCCTCTCATCCAGCTGAGGCTCTGGCCACACC
  TGCCAAGGGGCTTCTACCTCCCTGGGAATCTGAGATAACTGGCTCTTGCACAGCAAGGTG
  ACCCAAATGACACACCCGGGCTAATTGAGCCCTTTCCGGCATTTTCGCAAACACCTGTTC
  TTTAGGCCTGCTTTGGGAGGGCCCCCCCCCCCCGCCCTGTTTGATTTAACCTCTTCCCGC
  GCCATTCCCGCGTTCCGCCCCCCAAAAGCCCATTTGGACCGGCCCCCCCTCTCATTTATG
  GCCGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006058
• Insert Size: 3000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006058.2, NP_006049.2
• RefSeq Size: 2921 bp
• RefSeq ORF: 1911 bp
• Locus ID: 10318
• UniProt ID: Q15025
• Cytogenetics: 5q33.1
• Gene Summary: This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  Transcript Variant: This variant (5) uses an alternate splice site in the 3' coding region, compared to variant 1. The resulting isoform (3) is longer and contains a distinct Cz-terminus, compared to isoform 1. Variants 3, 4, 5 and 8 encode the same protein (isoform 3).