TAC1 (NM_013996) Human Untagged Clone

CAT#: SC115205

TAC1 (untagged)-Human tachykinin, precursor 1 (TAC1), transcript variant alpha

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TAC1
• Synonyms: Hs.2563; NK2; NKNA; NPK; TAC2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115205 sequence for NM_013996 edited (data generated by NextGen Sequencing)
  ATGAAAATCCTCGTGGCCTTGGCAGTCTTTTTTCTTGTCTCCACTCAGCTGTTTGCAGAA
  GAAATAGGAGCCAATGATGATCTGAATTACTGGTCCGACTGGTACGACAGCGACCAGATC
  AAGGAGGAACTGCCGGAGCCCTTTGAGCATCTTCTGCAGAGAATCGCCCGGAGACCCAAG
  CCTCAGCAGTTCTTTGGATTAATGGGCAAACGGGATGCTGATTCCTCAATTGAAAAACAA
  GTGGCCCTGTTAAAGGCTCTTTATGGACATGGCCAGATCTCTCACAAAATGGCTTATGAA
  AGGAGTGCAATGCAGAATTATGAAAGAAGACGTTAA
  
  Clone variation with respect to NM_013996.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013996 unedited
  TGTCANATTTGTATACGACTCATATAGGCGGCNCGCGAATCGGCACGAGGCACGCAAGCG
  AAAGGAGAGGAGGCGGCTAATTAAATATTGAGCAGAAAGTCGCGTGGGGAGAATGTCACG
  TGGGTCTGGAGGCTCAAGGAGGCTGGGATAAATACCGCAAGGCACTGAGCAGGCGAAAGA
  GCGCGCTCGGACCTCCTTCCCGGCGGCAGCTACCGAGAGTGCGGAGCGACCAGCGTGCGC
  TCGGAGGAACCAGAGAAACTCAGCACCCCGCGGGACTGTCCGTCGCAAAATCCAACATGA
  AAATCCTCGTGGCCTTGGCAGTCTTTTTTCTTGTCTCCACTCAGCTGTTTGCAGAAGAAA
  TAGGAGCCAATGATGATCTGAATTACTGGTCCGACTGGTACGACAGCGACCAGATCAAGG
  AGGAACTGCCGGAGCCCTTTGAGCATCTTCTGCAGAGAATCGCCCGGAGACCCAAGCCTC
  AGCAGTTCTTTGGATTAATGGGCAAACGGGATGCTGATTCCTCAATTGAAAAACAAGTGG
  CCCTGTTAAAGGCTCTTTATGGACATGGCCAGATCTCTCACAAAAGACATAAAACAGATT
  CCTTTGTTGGACTAATGGGCAAAAGAGCTTTAAATTCTGTGGCTTATGAAAGGAGTGCAA
  TGCAGAATTATGAAAGAAGACGTTAATAAACTACCTAACATTATTTATTCAGCTTCATTT
  GTGTATATGGGCAATGACAGGTAAATTAAGACATGCACTATGAGGAATAATTATTTATTT
  AATAACAATTGTTTGGGGTTGAAAATTCCATAAGTGTTTATTTTTCATATTGTGCCAATA
  TGTATTGTAAACATGTGTTTTAATTCCCATATGATGACTCCCTTAAACTAGNNAATAGTG
  NTATTCCTCACAAAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_013996 unedited
  ATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTCAAAATATTTTTTCTTTTATTT
  AAAATGTTAGCTATCACAACACATCATACAATGAAATGAAGACTTTAGAATCACATTGAA
  ACTTTTAAAAACATCTTTATATAGTCACAAAACATGAAACATGCTTCAAAGATACAAATA
  CAGGGTAATACCAAAATCTCAGTACATTTTCACCATGAAAACAAATAGGAAAAGCACAAG
  ACTGTCAGGAGTTTCCTTCCTTTTCCGCAGTAGCTGACACAACTGCTTCAAAGCAATGAT
  TTTTTTTCTTTAGGGACTGTATCATTGACAGGTTTTACAATTTCATTTAACACTGTGCTT
  TGTTGAAAAATAACCACTTATTTCTATTTTAAGGGAGTCATCATATTGGAATTAAAACAC
  ATGTTTACAATACATATTGGCACAATATGAAAAATAAACACTTTTTGAATTTTCAACCCC
  AAACAATGGTTATTAAATAAATAATTATTCCTCATAGTGCATGTCTTAATTTACCTGTCA
  TTGCCCATTGACACAAATGAAGCTGAATAAATAATGTTAGGTAGTTAATTAACGTCTTCT
  TTATAATTCTGCATTGCACTCCTTTCATAAGCCACAGAAATTAAAGCTCTTTTGCCCATT
  AGTCCAACAAAGGAATCTGTTTTATGTCTTTTGTGAGAGATCTGGGCATGTCCATAAAGA
  GCCTTTACAGGGCCACTTGTTTTTCAATGGAGGATCAGCATCCCGTTGGCCCATAATCCA
  ANGACTGCTGAGGCTGGGTCTCCCGGCGATTCTTTGCAAAATAGCTCAAAGGCCTCCGGA
  GTTTCTCCTTGATCTGGCGCTGCNGCCCAGCCCGAACANAATCACGACATCATGGGCTCT
  TATTTTTTGCAACAGTGAGGGAAACAAAAAAAACTGCAAGGCCACAGATTTCTGTTGGAT
  TTGCACAGAAGCCCCGGGGTGCTGTTTTTTGTTCTTCAAGCGACCGTCGCTCCGCTTCGG
  AG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_013996
• Insert Size: 1260 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_013996.1, NP_054702.1
• RefSeq Size: 1048 bp
• RefSeq ORF: 336 bp
• Locus ID: 6863
• UniProt ID: P20366
• Cytogenetics: 7q21.3
• Domains: Tachykinin
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
  Transcript Variant: As compared to the full-length transcript variant beta, variant alpha lacks exon 6, and therefore does not encode neuropeptide K, neurokinin A, or neuropeptide gamma. This transcript does encode the hormone substance P located on exon 3.