KCNE3 (NM_005472) Human Untagged Clone

CAT#: SC111131

KCNE3 (untagged)-Human potassium voltage-gated channel, Isk-related family, member 3 (KCNE3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNE3
• Synonyms: BRGDA6; HOKPP; HYPP; MiRP2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005472, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGACTACCAATGGAACGGAGACCTGGTATGAGAGCCTGCATGCCGTGCTGAAGGCTCTAAATGCCA
  CTCTTCACAGCAATTTGCTCTGCCGGCCAGGGCCAGGGCTGGGGCCAGACAACCAGACTGAAGAGAGGCG
  GGCCAGCCTACCTGGCCGTGATGACAACTCCTACATGTACATTCTCTTTGTCATGTTTCTATTTGCTGTA
  ACTGTGGGCAGCCTCATCCTGGGATACACCCGCTCCCGCAAAGTGGACAAGCGTAGTGACCCCTATCATG
  TGTATATCAAGAACCGTGTGTCTATGATCTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005472 unedited
  NGGTTGTCGNAATTTGTATACGACTCCTATAGGCGGCCGCGNATTCGGCACCAGCCGGGG
  NAGAGTGGGTGTGCTGGGGCCCGGGCGGGGCAGGGGGAGGGGACGCCCGGGGGAGGGAAA
  AGGGAGCCGAGCGCGGGTGGGAGCCCAGAGCCAGAGAGCGCGCTGGGCGGTGCTGGGCAC
  CCGCGGAGTGGAACGGGGCTGGTGGAATGCACAGGGTCGCAGCGCTTGGGCCACCCTCGG
  TCAGAGGGCGCCGTGTCCAGCGAGCAAACGGGCGCCCCGGAGCCTTGCTGAGAGGCAGCT
  CTGGGCTTTCCCAGCTCCGAAGTCAATACTGAGATCCCAGATGTGTCCAGAGACATCCTG
  AAGAGGCTCGGGGGTGGAGGAGCCTTAGTGTGTCCACAAAGGGACTCCTGAAACTGACTG
  AGAGCCAGTGGATTTGCCAGCAGTCTGAGCTTCTACCGAGTCTTCCCCCACCTCAATCCC
  TGTTGCTATGGAGACTACCAATGGAACGGAGACCTGGTATGAGAGCCTGCATGCCGTGCT
  GAAGGCTCTAAATGCCACTCTTCACAGCAATTTGCTCTGCCGGCCAGGGCCAGGGCTGGG
  GCCAGACAACCAGACTGAAGAGAGGCGGGCCAGCCTACCTGGCCGTGATGACAACTCCTA
  CATGTACATTCTCTTTGTCATGTTTCTATTTGCTGTAACTGTGGGCAGCCTCATCCTGGG
  ATACACCCGCTCCCGCAAAGTGGACAAGCGTAGTGACCCCTATCATGTGTATATCAAGAA
  CCGTGTGTCTATGATCTAACACGAGAGGGCTGTGACGGTGGAAGACCACAGACACCTGGG
  ATTGCGTCTGGGGCCTCCAGAACTCTGCTGTGGACTGCATCCAGTCTCAGTGTCCCTATC
  TGTAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005472 unedited
  ATGGACCGGCGGCCGCAATCTANAATCGAGTTTTTTTTTTTTTTTTTTTTCAAAAACCCA
  AAGGCTTTTATTTTTATTTTTTCAAAATAAAAGTACCTTTTTTCCTTTTATTATACAAGT
  AACATACTTACGGTCAAGTCAGTCAAATATTACATAAATTTATCATGCGGAAAGGGAAAA
  TCACCTATAACCCAATTCCTCAAAGATAACTGCTGTCAAAATATTATTTCAAAGTTCTGC
  TATACACAAATACGCATGTTTCAATGGGTACTTCCAGGGACCGCATGGAGATCCCTTAAG
  TTGAAACTGGACAAACAGAACAGTGGATGGTTCTAGCTGAGATCTGGGATAGTTTCTGAA
  TTCAGAAGTGTTCACCAGCCACATTGCATGTATTAGCTGGAACCATATATGAAACTACGA
  TACTCAGCTGTTTCTAACCTACAAACACAGTGATTACATATGGCTCAACTTAATGTATAT
  GAAGCCTAGAATGTCAGAACTGATAGAGCCTTAGAGACTTTCAAGTCTATTTCATTATGT
  TGAAGAGGAAAACGGATGAGGGAGAGAAGTGTCCAGCCTAAGATCATACATCACCTTAAG
  TGGTAGAATCAGGGCTGCTTCTCTTCCTACTGGACCATGTACCTGTCTCTCATACTCTGC
  TTCTTTTAATATAATAATAATTTAGGTGCGATATCAGNCTTTTTTGTTTTTGGTTTTCGT
  TTTTTTTTTGAGACGAGCCTTGGTCTGGCACCCAGNCTGGGATGCAGTGGCGTGAATCTT
  GGGTCAATGGACCCTCCACCTCCCGGGCCCAAACAATTTCTCCTGCCTAGGCTTCCCAGA
  ATGCTGGGAATACGGGCCCCCGCCCCCACGCCGGCCATTTTCTTCCTTCCCCTCAGTATA
  CCGCCCCCCCCTTCTCCTGCCCATTCGCGCCCCCCACTTTTCGCGCCGCCCGTTCGCCGC
  TCCCTCGTTCCCGTGTGGCCCCCACCGTTGTCCACCCTCTCCTCCCCTCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005472
• Insert Size: 3410 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005472.3, NP_005463.1
• RefSeq Size: 2534 bp
• RefSeq ORF: 312 bp
• Locus ID: 10008
• UniProt ID: Q9Y6H6
• Cytogenetics: 11q13.4
• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane
• Gene Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008]