SNRP70 (SNRNP70) (NM_001301069) Human Tagged ORF Clone

CAT#: RG238170

SNRNP70 (tGFP-tagged) - Human small nuclear ribonucleoprotein 70kDa (U1) (SNRNP70), transcript variant 2

Product Images

Circular map for RG238170

Specifications

Product Data

• Tag: TurboGFP
• Symbol: SNRP70
• Synonyms: RNPU1Z; RPU1; Snp1; SNRP70; U1-70K; U1AP; U1RNP; U170K
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG238170 representing NM_001301069.
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGACCCAGTTCCTGCCGCCCAACCTTCTGGCCCTCTTTGCCCCCCGTGACCCTATTCCATACCTGCCA
  CCCCTGGAGAAACTGCCACATGAAAAACACCACAATCAACCTTATTGTGGCATTGCGCCGTACATTCGA
  GAGTTTGAGGACCCTCGAGATGCCCCTCCTCCAACTCGTGCTGAAACCCGAGAGGAGCGCATGGAGAGG
  AAAAGACGGGAAAAGATTGAGCGGCGACAGCAAGAAGTGGAGACAGAGCTTAAAATGTGGGACCCTCAC
  AATGATCCCAATGCTCAGGGGGATGCCTTCAAGACTCTCTTCGTGGCGAGAGTGAATTATGACACAACA
  GAATCCAAGCTCCGGAGAGAGTTTGAGGTGTACGGACCTATCAAAAGAATACACATGGTCTACAGTAAG
  CGGTCAGGAAAGCCCCGTGGCTATGCCTTCATCGAGTACGAACACGAGCGAGACATGCACTCCGCTTAC
  AAACACGCAGATGGCAAGAAGATTGATGGCAGGAGGGTCCTTGTGGACGTGGAGAGGGGCCGAACCGTG
  AAGGGCTGGAGGCCCCGGCGGCTAGGAGGAGGCCTCGGTGGTACCAGAAGAGGAGGGGCTGATGTGAAC
  ATCCGGCATTCAGGCCGCGATGACACCTCCCGCTACGATGAGAGGGACCGGGACCGGGACCGTGAGCGG
  GAGCGCAGAGAGCGGAGCCGGGAGCGAGACAAGGAGCGAGAACGGCGACGCTCCCGCTCCCGGGACCGG
  CGGAGGCGCTCACGGAGTCGCGACAAGGAGGAGCGGAGGCGCTCCAGGGAGCGGAGCAAGGACAAGGAC
  CGGGACCGGAAGCGGCGAAGCAGCCGGAGTCGGGAGCGGGCCCGGCGGGAGCGGGAGCGCAAGGAGGAG
  CTGCGTGGCGGCGGTGGCGACATGGCGGAGCCCTCCGAGGCGGGTGACGCGCCCCCTGATGATGGGCCT
  CCAGGGGAGCTCGGGCCTGACGGCCCTGACGGTCCAGAGGAAAAGGGCCGGGATCGTGACCGGGAGCGA
  CGGCGGAGCCACCGGAGCGAGCGCGAGCGGCGCCGGGACCGGGATCGTGACCGTGACCGTGACCGCGAG
  CACAAACGGGGGGAGCGGGGCAGTGAGCGGGGCAGGGATGAGGCCCGAGGTGGGGGCGGTGGCCAGGAC
  AACGGGCTGGAGGGTCTGGGCAACGACAGCCGAGACATGTACATGGAGTCTGAGGGCGGCGACGGCTAC
  CTGGCTCCGGAGAATGGGTATTTGATGGAGGCTGCGCCGGAG
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC
  
  Protein Sequence

  >Peptide sequence encoded by RG238170
  Blue=ORF Red=Cloning site Green=Tag(s)
  
  MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMER
  KRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSK
  RSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVN
  IRHSGRDDTSRYDERDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKD
  RDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRER
  RRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMYMESEGGDGY
  LAPENGYLMEAAPE
  TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV
  MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED
  SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA
  FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV
  
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001301069
• ORF Size: 1284 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).

Reference Data

• RefSeq: NM_001301069.2
• RefSeq Size: 1981 bp
• RefSeq ORF: 1287 bp
• Locus ID: 6625
• UniProt ID: P08621
• Cytogenetics: 19q13.33
• Protein Families: Druggable Genome
• Protein Pathways: Spliceosome
• MW: 51.1 kDa
• Gene Summary: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome (PubMed:19325628, PubMed:25555158). SNRNP70 binds to the loop I region of U1-snRNA (PubMed:2467746, PubMed:19325628, PubMed:25555158).[UniProtKB/Swiss-Prot Function]