Human TNFRSF18/GITR ELISA Kit
USD 705.00
3 Weeks*
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Specifications
Product Data | |
Assay Type | Sandwich ELISA kit of Quantitative Detection for Human TNFRSF18/GITR |
Assay Length | 3.5 hours incubations; 1 hour washing and analyzing samples |
Signal | Colorimetric |
Curve Range | 62.5pg/ml-4000pg/ml |
Sample Type | Cell culture supernates, serum and plasma(heparin, EDTA). |
Sample Volume | 100 ul |
Specificity | This kit is used for quantitative detection of human TNFRSF18 |
Sensitivity | <10pg/ml |
Reactivities | Human |
Cross Reactivity | There is no detectable cross-reactivity with other relevant proteins. |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Tumor necrosis factor receptor superfamily member 18(TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. This gene is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Gene Symbol | TNFRSF18 |
Gene ID | 8784 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.