QDPR Rabbit Polyclonal Antibody

CAT#: TA365983

QDPR rabbit polyclonal antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-5: Mouse liver tissue Mouse brain tissue Rat brain tissue Rat liver tissue and Human fetal liver tissue lysates Primary antibody: TA365983 (QDPR Antibody) at dilution 1/800 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 30 seconds

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA365983 (QDPR Antibody) at dilution 1/70 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA365983 (QDPR Antibody) at dilution 1/70, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA365983 (QDPR Antibody) at dilution 1/70 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA365983 (QDPR Antibody) at dilution 1/70, treated with fusion protein. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse liver tissue, Mouse brain tissue, Rat brain tissue, Rat liver tissue and Human fetal liver tissue lysates
  IHC: 50-200
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human QDPR
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 26 kDa
• Gene Name: quinoid dihydropteridine reductase
• Database Link:
  Entrez Gene 5860 Human
  UniProt ID P09417
• Background: This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
• Synonyms: DHPR; FLJ42391; HDHPR; PKU2; SDR33C1