TPP1 Rabbit Polyclonal Antibody

CAT#: TA361227

TPP1 Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: TPP1 Sample Tissue: Human Lung Tumor lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TPP1
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 61 kDa
• Gene Name: tripeptidyl peptidase 1
• Database Link:
  NP_000382.3
  Entrez Gene 1200 Human
  UniProt ID O14773
• Background: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
• Synonyms: CLN2; GIG1; LPIC; MGC21297; TPP-1; TPP-I

Reference Data

• Protein Families: Protease
• Protein Pathways: Lysosome