PP2A-beta (PPP2CB) Rabbit Polyclonal Antibody

CAT#: TA323426

Anti-PPP2CB Rabbit Polyclonal Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane: Jurkat cells Primary antibody: TA323426 (PPP2CB Antibody) at dilution 1/1200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA323426 (PPP2CB Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA323426 (PPP2CB Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Jurkat cells
  IHC: 50-200
  Positive control: Human breast cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 292-306 amino acids of Human protein phosphatase 2, catalytic subunit, beta isozyme
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 36 kDa
• Gene Name: protein phosphatase 2 catalytic subunit beta
• Database Link:
  NP_001009552
  Entrez Gene 19053 MouseEntrez Gene 24673 RatEntrez Gene 5516 Human
  UniProt ID P62714
• Background: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases; and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme; which is composed of a catalytic subunit and a constant regulatory subunit; that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit.
• Synonyms: PP2Abeta; PP2CB

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Long-term depression, Oocyte meiosis, TGF-beta signaling pathway, Tight junction, Wnt signaling pathway