GPBB (PYGB) Rabbit Polyclonal Antibody

CAT#: TA322941

Anti-PYGB Rabbit Polyclonal Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: HT29 cells Primary antibody: TA322941 (PYGB Antibody) at dilution 1/550 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: HT-29 cells
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 1-15 amino acids of Human phosphorylase, glycogen; brain
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 97 kDa
• Gene Name: phosphorylase, glycogen; brain
• Database Link:
  NP_002853
  Entrez Gene 25739 RatEntrez Gene 110078 MouseEntrez Gene 5834 Human
  UniProt ID P11216
• Background: The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers; the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP; ADP; and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation
• Synonyms: GPBB

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Insulin signaling pathway, Starch and sucrose metabolism