Ido1 Mouse Monoclonal Antibody [Clone ID: 2E2.6]

CAT#: TA319586

Mouse monoclonal anti-IDO1 antibody


USD 780.00

In Stock*

Size
    • 100 ug

Frequently bought together (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 200.00

Other products for "Ido1"

Specifications

Product Data
Clone Name 2E2.6
Applications FC, IF, IHC, WB
Recommended Dilution ELISA: 1:5000-1:50000, WB: 1:500-1:1500, IF: 1:50-1:100, IP: 10-100 uL, FC: 0.5-1x10^6 cells
Reactivities Mouse
Host Mouse
Clonality Monoclonal
Immunogen IDO1 antibody was produced in mouse by repeated immunizations with mouse recombinant IDO1 protein followed by hybridoma development.
Formulation 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Concentration lot specific
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name indoleamine 2,3-dioxygenase 1
Synonyms CD107B; IDO; INDO
Note Anti-IDO-1 antibody recognizes indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.
Reference Data

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