SREBP1 (SREBF1) Mouse Monoclonal Antibody [Clone ID: 2A4]

CAT#: TA309880

Mouse Monoclonal SREBP1 Antibody (2A4)

Product Images

Simple Western: SREBP1 Antibody (2A4) TA309880 - Lane view shows a specific band for SREBP1 in 1.0 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.

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  Knockout Validated: SREBP1 Antibody (2A4) TA309880 - KO and OE of SREBP1 influenced lipid metabolism in Bel-7402 cells. The protein level of lipid-associated genes in SREBP1-KO, SREBP1-OE, and WT Bel-7402 cells. Data were expressed as mean -/+ standard error of the mean. *P < 0.05, **P < 0.01, and ***P < 0.001 vs. WT group, respectively.

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  Western Blot: SREBP1 Antibody (2A4) TA309880 - Analysis of whole cell lysate from HeLa cells showing a single specific band for the expression of SREBP1 precursor protein (~120 kDa).

Specifications

Product Data

• Clone Name: 2A4
• Applications: IHC, Simple Western, WB
• Recommended Dilution: Western Blot: 1-2ug/ml, Simple Western: 1:12.5, Knockout Validated, Immunohistochemistry-Frozen
• Reactivities: Human, Mouse, Rat, Golden Syrian Hamster
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: 6 His-tag fusion protein of SREBP1 corresponding to amino acids 301-407
• Formulation: Tris-glycine, 150mM NaCl and 0.05% Sodium Azide
• Concentration: lot specific
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: sterol regulatory element binding transcription factor 1
• Database Link:
  NP_004167
  Entrez Gene 20787 MouseEntrez Gene 78968 RatEntrez Gene 6720 Human
  UniProt ID P36956
• Synonyms: bHLHd1; SREBP-1c; SREBP1; SREBP1a

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Insulin signaling pathway