PLEKHM2 Rabbit Polyclonal Antibody

CAT#: TA306874

Rabbit Polyclonal PLEKHM2 Antibody

Product Images

Western blot analysis of PLEKHM2 in rat brain tissue lysate with PLEKHM2 antibody at 0.5 ug/ml in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of FAM59A in human liver tissue with FAM59A antibody at 5 ug/ml.

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  Immunofluorescence of PLEKHM2 in Human Brain cells with PLEKHM2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 0.5 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: PLEKHM2 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human PLEKHM2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: pleckstrin homology and RUN domain containing M2
• Database Link:
  NP_055979
  Entrez Gene 69582 MouseEntrez Gene 313667 RatEntrez Gene 23207 Human
  UniProt ID Q8IWE5
• Background: PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.
• Synonyms: SKIP

Reference Data

• Protein Families: Druggable Genome