Hepatitis B Surface Antigen / HBsAg Mouse Monoclonal Antibody [Clone ID: HB3]

CAT#: SM3109P

Hepatitis B Surface Antigen / HBsAg mouse monoclonal antibody, clone HB3, Purified

Specifications

Product Data

• Clone Name: HB3
• Applications: ELISA, IF
• Recommended Dilution: ELISA.
  Immunocytochemistry.
  
• Reactivities: Hepatitis B Virus
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified HbsAg from Human plasma.
• Specificity: The antibody HB3 recognizes following Hepatitis B virus subtypes: ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-.
  Specificity of the antibody HB3 was verified by ELISA on panel of virus subtypes identified on International Workshop on HBsAg Subtypes (Paris, April 1975).
  The antibody HB3 does not cross-block with the antibody HB5.
• Formulation: Phosphate Buffered Saline (PBS), pH~7.4
  State: Purified
  State: Liquid purified Ig fraction from Ascites (> 95% by SDS-PAGE)
  Preservative: 15 mM Sodium Azide
• Concentration: lot specific
• Purification: Pecipitation Methods and Ion Exchange Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  
• Stability: Shelf life: one year from despatch.
• Background: HBsAg (Hepatitis B surface antigen) is a marker of infectivity. Its presence indicates either acute or chronic HBV infection.
  Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
• Synonyms: HBV surface antigen, Hepatitis B Virus