Alpha 1 microglobulin (AMBP) Sheep Polyclonal Antibody

CAT#: BP631P

Alpha 1 microglobulin (AMBP) sheep polyclonal antibody, Purified

Specifications

Product Data

• Applications: ELISA, ID
• Recommended Dilution: ELISA: 1/500-1/1000.
  Immunodiffusion.
• Reactivities: Human
• Host: Sheep
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Highly pure human alpha-1-microglobulin, prepared from the urine of patients with chronic renal proteinuria (Molecular Weight 25-30 kD).
• Specificity: This antibody recognises human alpha-1-microglobulin.
  No cross-reactivity is observed with urine Albumin, Retinol binding protein or beta-2-Microglobulin.
  It does NOT react with Rat.
• Formulation: PBS containing 0.09% Sodium Azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: alpha-1-microglobulin/bikunin precursor
• Database Link:
  Entrez Gene 259 Human
  UniProt ID P02760
• Background: Alpha(1)microglobulin/bikunin precursor specifically interacts with the ORF3 protein of hepatitis E virus and has a direct role in enhancing alpha(1)microglobulin export from the hepatocyte. Bikunin has a role in downregulating PI3 kinase and suppressing tumor invasiveness and metastasis in ovaran cancer cells. I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin. Interacts with FN1
• Synonyms: Alpha-1-microglobulin, HCP, Inter-alpha-trypsin inhibitor light chain, ITI-LC, ITIL, Bikunin, HI-30, EDC1, Trypstatin