Melanocyte Stimulating Hormone / MSH alpha Rabbit Polyclonal Antibody

CAT#: BP5037

Melanocyte Stimulating Hormone / MSH alpha rabbit polyclonal antibody, Serum

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Frozen Sections.
  Immunohistochemistry on Paraffin Sections.
  Recommended Dilutions: 1/200-1/400, 1 h at room temperature using FITC.
  Positive Control: Bouin-fixed paraffin sections of pig putuitary.
• Reactivities: Human, Porcine, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic alpha-MSH conjugated to BSA.
• Specificity: Specific for alpha-melanocyte stimulating hormone.
  Absorption with 10-100 µg immunogen per ml diluted antiserum abolishes the staining.
  In man, alpha-MSH is found in corticotrophs of the anterior pituitary and may also occur in brain neurons.
• Formulation: State: Serum
  State: Lyophilized serum
• Reconstitution Method: Dissolve the antiserum in 50-100 µl distilled water and dilute further in PBS with 1% BSA and 0.09% Sodium Azide.
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Background: Melanocyte-stimulating hormone belongs to a group called the melanocortins. This group includes ACTH, alpha-MSH, beta-MSH and gamma-MSH; these peptides are all cleavage products of a large precursor peptide called pro-opiomelanocortin (POMC). Alpha-MSH is the most important melanocortin for pigmentation. It increases the pigmentation of skin by increasing melanin production in melanocytes.