CD32B (FCGR2B) pTyr292 Rabbit Polyclonal Antibody
Other products for "FCGR2B"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western blot: 1:500~1:1000. |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32 (KLH-conjugated) |
Specificity | The antibody detects endogenous levels of CD32 only when phosphorylated at tyrosine 292. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography using epitope-specific peptide |
Conjugation | Unconjugated |
Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 32 kDa |
Gene Name | Fc fragment of IgG receptor IIb |
Database Link | |
Background | Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. |
Synonyms | FCGR2B, FCG2, IGFR2, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b |
Reference Data |
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