CRMP4 (DPYSL3) Rabbit Polyclonal Antibody

CAT#: AP54860PU-N

CRMP4 (DPYSL3) rabbit polyclonal antibody, Purified

Product Images

Immunoblot analysis of the specificity of CRMP4 antibody Cat.-No AP54860PU-N using E.coli lysate transformed with cDNA of Human CRMP4

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution:

  ELISA.
  Western Blot: 1/2000.
  Immunohistochemistry: 1/500.

• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: A 15 residue synthetic peptide derived from C-terminal domain of Human Collapsing-Response Mediator.
• Specificity: Reacts with 65 kDa CRMP-4.
  This antibody does not react with CRMP-1, CRMP-2, CRMP-3 or CRMP-5.
• Formulation: 0.1M Tris, 0.1M Glycine, 2% Sucrose
  State: Purified
  State: Lyophilized purified antibody
  Preservative: None
• Reconstitution Method: Restore in distilled water.
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: dihydropyrimidinase like 3
• Database Link:
  Entrez Gene 1809 Human
  UniProt ID Q14195
• Background: The collapsin response mediator protein (CRMP) family of five cytosolic phosphoproteins are highly expressed throughout brain development. The functions of CRMPs encompass signal transduction in developmental guidance cues as well as multiple cellular and molecular events involved in apoptosis/proliferation, cell migration, and differentiation. In the adult brain, the expression of CRMPs is dramatically downregulated. However, CRMPs remain expressed in structures that retain their capacity for differentiation and plasticity. The expression of CRMPs is altered in neurodegenerative diseases, and these proteins may have a role in the physiopathology of the adult nervous system.
• Synonyms: CRMP-4, DRP3, DRP-3, ULIP, ULIP1, ULIP-1, TUC-4