MRC2 (Center) Rabbit Polyclonal Antibody

CAT#: AP52744PU-N

MRC2 (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in NCI-H460 cell line lysates (35ug/lane) using CD280 / MRC2 antibody. This demonstrates this antibody detected the MRC2 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/100-1/500.
  
  
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 797-827aa) of human C280 / MRC2.
• Specificity: This antibody recognizes CD280 /MRC2.
• Formulation: PBS with 0.09% (W/V) Sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a Protein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: mannose receptor C type 2
• Database Link:
  Entrez Gene 9902 Human
  UniProt ID Q9UBG0
• Background: MRC2 is a recycling endocytic receptor that functions in cell motility and remodeling of the extracellular matrix by promoting cell migration and uptake of collagens for intracellular degradation [Wienke et al., 2007; PubMed 17974964]
• Synonyms: C-type mannose receptor 2, ENDO180, KIAA0709, UPARAP, UPAR-associated protein, Urokinase receptor-associated protein, Endocytic receptor 180, Macrophage mannose receptor 2
• Note: Molecular Weight: 166655 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane