DEF6 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51230PU-N

DEF6 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

western blot analysis of DEF6 Antibody (C-term) in A375 cell line lysates (35ug/lane). This demonstrates the DEF6 antibody detected the DEF6 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 499-528 amino acids from the C-terminal region of human DEF6
• Specificity: This antibody recognizes Human DEF6 (C-term).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: DEF6, guanine nucleotide exchange factor
• Database Link:
  Entrez Gene 50619 Human
  UniProt ID Q9H4E7
• Background:
  DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).
• Synonyms: IBP, DEF-6, IRF4-binding protein, SLAT, SWAP70L
• Note: Molecular Weight: 73910 Da

Reference Data

• Protein Families: Druggable Genome