CRHBP (N-term) Rabbit Polyclonal Antibody

CAT#: AP51082PU-N

CRHBP (N-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of CRHBP (arrow) using rabbit polyclonal CRHBP Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CRHBP gene.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human CRHBP
• Specificity: This antibody reacts to human CRHBP.
• Formulation: PBS
  State: Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 36144 Da
• Gene Name: corticotropin releasing hormone binding protein
• Database Link:
  Entrez Gene 1393 Human
  UniProt ID P24387
• Background: Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.
• Synonyms: CRF-binding protein, CRF-BP, CRFBP