CPS1 (N-term) Rabbit Polyclonal Antibody

CAT#: AP51056PU-N

CPS1 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CPS1 Antibody (N-term) in Hela cell line lysates (35ug/lane).This demonstrates the CPS1 antibody detected the CPS1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/1000.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 262-291 amino acids from the N-terminal region of Human CPS1
• Specificity: This antibody recognizes Human CPS1 (N-term). Other species not tested.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: carbamoyl-phosphate synthase 1
• Database Link:
  Entrez Gene 1373 Human
  UniProt ID P31327
• Background:
  The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
• Synonyms: CPSase I
• Note: Molecular Weight: 164939 Da