Factor D (CFD) (N-term) Rabbit Polyclonal Antibody

CAT#: AP50877PU-N

Factor D (CFD) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CFD Antibody (N-term) in A549 cell line lysates (35ug/lane). This demonstrates the CFD antibody detected the CFD protein (arrow).

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  Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human bladder carcinoma stained with CFD Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of CFD Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100-1/500.
  Immunohistochemistry: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 75-107 amino acids from the N-terminal region of Human CFD
• Specificity: Recognizes CFD (N-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column followed by peptide Affinity purification
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: complement factor D
• Database Link:
  Entrez Gene 1675 Human
  UniProt ID P00746
• Background: The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
• Synonyms: Properdin factor D, Adipsin, CFD, DF, PFD
• Note: Molecular Weight: 27033 Da

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Complement and coagulation cascades