SnoN (SKIL) Rabbit Polyclonal Antibody

CAT#: AP20409PU-N

SnoN (SKIL) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of SnoN antibody (Cat.-No.: AP20409PU-N) in extracts from HUVEC cells.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/500-1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of SnoN protein.
  (region surrounding Asp652)
• Formulation: Phosphate buffered saline (PBS), pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 77 kDa
• Gene Name: SKI-like proto-oncogene
• Database Link:
  Entrez Gene 6498 Human
  UniProt ID P12757
• Background: SnoN may have a regulatory role in cell division or differentiation in response to extracellular signals. SnoN acts as a positive mediator of TGF beta induced transcription and cell cycle arrest in lung epithelial cells. The ability of SnoN to repress the growth inhibitory function of the Smad proteins is required for their transforming activity.
• Synonyms: Ski-like protein, Ski-related protein, Ski-related novel protein N, Ski-related oncogene, SNO, SnoA, Snol