IL1 alpha (IL1A) Rabbit Polyclonal Antibody

CAT#: AP17498PU-N

IL1 alpha (IL1A) rabbit polyclonal antibody

Product Images

Western blot analysis of IL1A (arrow) using rabbit polyclonal IL1A-pS87. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the IL1A gene (Lane 2) (Origene Technologies).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the amino acid residues surrounding S87 of human IL1A
• Specificity: This antibody reacts to IL-1 alpha.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: interleukin 1 alpha
• Database Link:
  Entrez Gene 3552 Human
  UniProt ID P01583
• Background: IL1A is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis.
• Synonyms: IL-1 alpha, IL1F1, IL1A, Hematopoietin-1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, Prion diseases, Type I diabetes mellitus