PIP5K2 alpha (PIP4K2A) (N-term) Rabbit Polyclonal Antibody

CAT#: AP14966PU-N

PIP5K2 alpha (PIP4K2A) (N-term) rabbit polyclonal antibody, Purified

Product Images

The anti-PIP5K2A Pab is used in Western blot to detect PIP5K2A in mouse skeletal muscle tissue lysate.

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  Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/100 - 1/500.
  Immunohistochemistry: 1/50 - 1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PIP5K2A.
• Specificity: This antibody reacts to PIP5K2 alpha.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Purified polyclonal antibody supplied in . This antibody is purified through a
• Concentration: lot specific
• Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
• Database Link:
  Entrez Gene 5305 Human
  UniProt ID P48426
• Background: Phosphatidylinositol-4,5-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. TPIP5K2A is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. The protein is a member of the phosphatidylinositol-4-phosphate 5-kinase family.
• Synonyms: PIP4KII-alpha, PIP5K2, PIP5KIII, Diphosphoinositide kinase 2-alpha, PtdIns(4)P-5-kinase B isoform, PtdIns(4)P-5-kinase C isoform, PtdIns(5)P-4-kinase isoform 2-alpha