AMPK alpha 1 (PRKAA1) Rabbit Polyclonal Antibody
Other products for "PRKAA1"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA 1:1,000. Western blot 1:50 - 1:100. Immunohistochemistry 1:10 - 1:50. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S487 of human PRKAA1. |
Specificity | This antibody detects AMPK alpha (PRKAA1). |
Formulation | PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification. |
Conjugation | Unconjugated |
Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | protein kinase AMP-activated catalytic subunit alpha 1 |
Database Link | |
Background | PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. |
Synonyms | AMPK1, AMPK alpha-1 chain |
Note | Molecular weight: 63878 Da |
Reference Data |
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