PINK1 Rabbit Polyclonal Antibody
Other products for "PINK1"
Specifications
Product Data | |
Applications | ELISA, IHC, WB |
Recommended Dilution | ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide in the N-terminal region of human Park6 (PINK1). |
Specificity | This antibody reacts to PINK1 (PARK6). |
Formulation | PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid purified Ig |
Concentration | lot specific |
Purification | Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | PTEN induced putative kinase 1 |
Database Link | |
Background | Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD. |
Synonyms | PTEN-induced putative kinase protein 1, PARK6, BRPK, PINK-1 |
Reference Data |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.