NFAT1 (NFATC2) pSer330 Rabbit Polyclonal Antibody
Other products for "NFATC2"
Specifications
Product Data | |
Recommended Dilution | ELISA: 1/1,000. Dot Blot: 1/500. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S330 of human NFATC2. |
Specificity | This antibody detects NFATC2 pSer330. |
Formulation | PBS with 0.09% (W/V) Sodium Azide as preservative. State: Aff - Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Protein A Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | nuclear factor of activated T-cells 2 |
Database Link | |
Background | NFATC2 is a member of the nuclear factor of activated T cells (NFAT) family. It is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. |
Synonyms | NFATC2, NFAT-1, NFATP |
Note | Molecular weight: 99654 Da |
Reference Data |
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