ENPP2 (Center) Rabbit Polyclonal Antibody

CAT#: AP12517PU-N

ENPP2 (Center) rabbit polyclonal antibody, Purified

Product Images

(LEFT) Western blot analysis of anti-ENPP2 Antibody (Center) in Y79 cell line lysates (35ug/lane). ENPP2 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of anti-ENPP2 Antibody (Center K416) in mouse cerebellum tissue lysates (35ug/lane).ENPP2 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western Blot: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human ENPP2.
• Specificity: This antibody detects Autotaxin/ENPP2 (Center).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
• Database Link:
  Entrez Gene 5168 Human
  UniProt ID Q13822
• Background: ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. This protein is secreted and further processed to make the biologically active form.
• Synonyms: E-NPP 2, ENPP2, ATX, PDNP2
• Note: Molecular weight: 99004 Da