5HT6 Receptor (HTR6) (C-term) Rabbit Polyclonal Antibody

CAT#: AP10420PU-N

5HT6 Receptor (HTR6) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 2.5 - 5 µg/ml.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: HTR6 / 5-HT6 Receptor antibody was raised against synthetic 17 amino acid peptide from C-terminus of human HTR6 / 5-HT6.
  Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla (100%); Monkey, Horse (94%); Gibbon, Dog, Rabbit (88%); Elephant (82%).
• Specificity: The antibody recognizes the human Serotonin (5-hydroxytryptamine) receptor 6. Other species not tested.
  Epitope: C-terminal domain of human.
• Formulation: PBS, pH 7.7, containing 0.09% sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Peptide immunogen affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: 5-hydroxytryptamine receptor 6
• Database Link:
  Entrez Gene 3362 Human
  UniProt ID P50406
• Background: 5-HT6 (HTR6) is a receptor for 5-hydroxytryptamine (Serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. 5-HT6 has been reported primarily in striatum of the brain. Expression has also been seen in stomach, spinal cord, and the lymphoid tissues of rats, including peripheral blood lymphocytes, spleen, and thymus.
• Synonyms: 5-hydroxytryptamine receptor 6, 5-HT-6

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction