PINX1 (225-237) Goat Polyclonal Antibody

CAT#: AP10037PU-N

PINX1 (225-237) goat polyclonal antibody, Aff - Purified

Product Images

Anti-PINX1 (0.3ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: Peptide ELISA: 1/16000.
  Western blot: Approx 40kDa band observed in lysates of cell lines A549, HepG2 and K562 (calculated MW of 37.0kDa according to NP_060354.4).
  Recommended concentration: 0.3 - 1.0 µg/ml.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-ESYLQPKAKRHTE, from the internal region of the protein sequence according to NP_060354.4.
• Specificity: This antibody reacts to PINX1.
• Formulation: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: PIN2/TERF1 interacting, telomerase inhibitor 1
• Database Link:
  Entrez Gene 54984 Human
  UniProt ID Q96BK5
• Background: PINX1 (PIN2-interacting protein 1) is a ubiquitously expressed protein that localizes to nucleoli and telomere speckles. It contains a TID (telomerase inhibiting domain) domain which is capable of binding MCRS1, TERT and TERF1 and has been shown to be a potent telomerase inhibitor and putative tumor suppressor.
• Synonyms: Pin2-interacting protein X1, LPTL, LPTS