PPP2R1A Sheep Polyclonal Antibody

CAT#: AP05040PU-N

PPP2R1A sheep polyclonal antibody, Purified

Product Images

Western Blot analysis: PPP2R1A antibody staining of total Rat brain homogenate.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1-5 µg.
  Immunocytochemistry: 1/500-1/1000.
  Immunoprecipitation often used in combination with Ig purified anti pp2A/C to immunoprecipitate heterotrimeric pp2A.
• Reactivities: Bovine, Human, Mouse, Rat
• Host: Sheep
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A peptide conjugated to KLH corresponding to amino acids 7-19 sequence (N-terminal) of PP2A/A regulatory subunit having a MW of 65kD
• Specificity: This antibody recognizes Serine/Threonine Protein Phosphatase 2A/A.
• Formulation: PBS pH 7.4 and 0.08% Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: protein phosphatase 2 scaffold subunit Aalpha
• Database Link:
  Entrez Gene 51792 MouseEntrez Gene 117281 RatEntrez Gene 5518 Human
  UniProt ID P30153
• Background: Protein phosphatase 2A (PP2A) is the most abundant phosphatase specific for serine and threonine phosphorylation in mammalian cells. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit alpha (PPP2R1A) serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory beta subunit.
• Synonyms: Protein phosphatase 2A, PP2A subunit A PR65-alpha isoform, PP2A subunit A R1-alpha isoform
• Note: Predicted Molecular Weight: 65 kDa

Reference Data

• Protein Families: Druggable Genome, Phosphatase, Transcription Factors
• Protein Pathways: Long-term depression, Oocyte meiosis, TGF-beta signaling pathway, Tight junction, Wnt signaling pathway