Natriuretic Peptide Receptor C (NPR3) (199-213) Rabbit Polyclonal Antibody

CAT#: AP02131SU-S

Natriuretic Peptide Receptor C (NPR3) (199-213) rabbit polyclonal antibody, Serum

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot (1/1000).
  Immunocytochemistry: 1/800.
  Immunofluorescence on Cryosections: 1/800.
• Reactivities: Human, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic Human NPR-C (199-213) poly Lysin conjugated
• Specificity: This antibody detects synthetic Human NPR-C (aa 199-213), Rat NPR-C.
• Formulation: State: Serum
  State: Lyophilized Serum
• Reconstitution Method: Restore in aqua bidest to initial volume.
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C and reconstituted at -20°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: natriuretic peptide receptor 3
• Database Link:
  Entrez Gene 4883 Human
  UniProt ID P17342
• Background: The family of natriuretic peptides elicits a number of vascular, renal and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal and brain.
  Natriuretic peptide receptor C does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction.
• Synonyms: Atrial natriuretic peptide C-type receptor, ANP clearance receptor, ANP-C, NPR-C
• Note: LocusID 4883