GAS 6 (GAS6) Rabbit Polyclonal Antibody

CAT#: AP01178PU-N

GAS 6 (GAS6) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Gas6 antibody in extracts from 293 cells.

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  Immunohistochemistry (IHC) analyzes of Gas6 antibody in paraffin-embedded human brain tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/1000.
  Immunohistochemistry on paraffin sections: 1/50 - 1/200.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 278-328 of Human Gas6.
• Specificity: This antibody detects endogenous levels of Gas6 protein. (region surrounding Gly309)
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Predicted Protein Size: ~ 80 kDa
• Gene Name: growth arrest specific 6
• Database Link:
  Entrez Gene 2621 Human
  UniProt ID Q14393
• Background: Growth arrest specific proteins, including Gas1 and Gas6, are activated in quiescent cells. Gas1-induced growth arrest is mediated by p53, and Gas1 appears to be able to suppress tumor cell growth. Gas6, a ligand for the tyrosine kinase receptor Axl, was initially identified as a member of the vitamin K-dependent protein family and exhibits a high degree of amino acid sequence homology to protein S, a negative co-regulator in the coagulation pathway.
• Synonyms: Growth arrest-specific protein 6, GAS-6