LRRC32 Mouse Monoclonal Antibody [Clone ID: GARP5]

CAT#: AM26772PU-N

LRRC32 mouse monoclonal antibody, clone GARP5, Purified

Product Images

Western Blotting analysis (reducing conditions) of GARP antigen and its degradatory products in lysate of human thrombocytes by anti-GARP monoclonal antibody (GARP5).

Specifications

Product Data

• Clone Name: GARP5
• Applications: WB
• Recommended Dilution: Western blot: 1-2 µg/ml
  positive control: human thrombocytes, reducing conditions
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified human sGARP protein
• Specificity: This antibody recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.
• Formulation: Phosphate buffered saline (PBS)
  State: Purified
  State: Liquid Ig fraction
  Preservative: 15 mM sodium azide, approx. pH 7.4
• Concentration: lot specific
• Purification: Protein-A affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  
• Stability: Shelf life: one year from despatch.
• Gene Name: leucine rich repeat containing 32
• Database Link:
  Entrez Gene 2615 Human
  UniProt ID Q14392
• Background: GARP (glycoprotein A repetitions predominant protein), also known as Garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.
• Synonyms: Garpin, D11S833E