Klra6 Mouse Monoclonal Antibody [Clone ID: HBF-719]

CAT#: AM08066RP-N

Klra6 mouse monoclonal antibody, clone HBF-719, PE

Specifications

Product Data

• Clone Name: HBF-719
• Applications: FC
• Recommended Dilution: Flow Cytometry: < / = 0.2 µg/10e6 cells. (Ref.1,3)
• Reactivities: Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: CHO cells transfected with the B6 allele of Ly49F. (Ref.1)
• Specificity: This antibody HBF-719 reacts with the B6 allele of Ly49F.
  It stains ~ 11% of NK1.1+CD3- splenocytes, and 3.5% (2.5 month old) to 10.0% (11 month old) of CD8+ spleen cells from C57BL/6 mice. (Ref.1)
• Formulation: PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent.
  Label: PE
  State: Liquid purified Ig fraction.
  Label: R-Phycoerythrin
• Concentration: lot specific
• Conjugation: PE
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
  This product is photosensitive and should be protected from light.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: killer cell lectin-like receptor, subfamily A, member 6
• Database Link:
  Entrez Gene 16637 Mouse
  UniProt ID Q60653
• Background: Ly49F is a member of the lectin like homodimeric Ly49 family of cell surface receptors. (Ref.1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down regulated. (Ref.2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells.
• Synonyms: Ly-49f, Ly49-f, Ly49F