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Anti-cyp7b1 TRUEMAB Antibody Clone OTI7E5
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for cyp7b1 (NM_004820)
|Human recombinant protein fragment corresponding to amino acids 350-506 of human Cyp7b1 (NP_004811) produced in E.coli.|
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens cytochrome P450, family 7, subfamily B, polypeptide 1 (CYP7B1)|
|CBAS3; CP7B; SPG5A|
Entrez Gene 9420 Human
|Cyp7b1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.|
|TransmembraneP450Druggable Genome Primary bile acid biosynthesis|
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-cyp7b1 monoclonal antibody.
Cyp7b1 antibody (7E5) at 1:500 dilution + lysates from HEK-293T transfected with human Cyp7b1 expression vector (Cat# RC222647)