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Home Antibody All anti-cyp7b1 antibodies

Anti-cyp7b1 TRUEMAB Antibody Clone OTI7E5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500050 Cyp7b1 mouse monoclonal antibody, clone OTI7E5 (formerly 7E5) 100ul $379 In Stock
LC417726 CYP7B1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500050 Carrier-free (BSA/glycerol-free) Cyp7b1 mouse monoclonal antibody, clone OTI7E5 (formerly 7E5) 100ug $450 3-4 weeks
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WB(2)
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Also for cyp7b1 (NM_004820)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 350-506 of human Cyp7b1 (NP_004811) produced in E.coli.
Clone NameClone OTI7E5 IsotypeIgG2b
Species ReactivityHuman, Monkey Concentration0.68 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:200~500,
Predicted MW Explanation 58.1 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cytochrome P450, family 7, subfamily B, polypeptide 1 (CYP7B1)
Alternative NameCBAS3; CP7B; SPG5A
Database LinkNP_004811
Entrez Gene 9420 Human
FunctionCyp7b1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
Related PathwayTransmembraneP450Druggable Genome Primary bile acid biosynthesis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-cyp7b1 monoclonal antibody.
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Cyp7b1 antibody (7E5) at 1:500 dilution + lysates from HEK-293T transfected with human Cyp7b1 expression vector (Cat# RC222647)
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