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Home Antibody All anti-ZFYVE9 antibodies

Anti-ZFYVE9 Antibody EPR5020

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311111
  • Rabbit Monoclonal antibody against SARA (ZFYVE9)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417734) , 20ug Explanation
100ul 325 3-7 Days
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WB(2)
IHC(1)
Assay(1)
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Also for ZFYVE9 (NM_004799)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues at the N-terminus of human SARA was used as an immunogen.
Clone NameEPR5020 IsotypeTissue culture supernatant
Species ReactivityRat, Human (Does not react with: Mouse) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; FC: 1:10 - 1:100
BufferDoes not react with Mouse. Is unsuitable for ICC.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for ICC.

Reference Data

Target NameHomo sapiens zinc finger, FYVE domain containing 9 (ZFYVE9), transcript variant 3
Alternative NameMADHIP; NSP; PPP1R173; SARA; SMADIP
Database LinkNP_004790
Entrez Gene 9372 Human
Entrez Gene 313477 Rat
FunctionSARA is a double zinc finger (FYVE domain) protein that interacts directly with SMAD2 and SMAD3, and is involved in Alzheimer's disease. SMAD proteins transmit signals from transmembrane serine/threonine kinase receptors to the nucleus. The FYVE domain has been identified in a number of unrelated signaling molecules. SARA functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE domain is required to maintain the normal localization of this protein but is not involved in mediating interaction with SMADs. The C-terminal domain of SARA interacts with the TGFB receptor. This protein is a component of the TGFB pathway that brings the SMAD substrate to the receptor (1).
Related Pathway TGF-beta signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-SARA antibody [EPR5020]; All lanes : Anti-SARA antibody [EPR5020] at 1/10000 dilution.Lane 1 : Human heart lysate.Lane 2 : A673 cell lysate.Lane 3 : HT-1080 cell lysate.Lane 4 : BxPC-3 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 156 kDa.
WB Image
Western blot - Anti-SARA antibody [EPR5020]; All lanes : Anti-SARA antibody [EPR5020] at 1/10000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : Human fetal brain lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 156 kDa.
Assay Image
Other-Anti-SARA antibody [EPR5020](TA311111); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SARA antibody [EPR5020]; Staining of SARA in Paraffin-embedded Human kidney tissue by Immunohistochemistry using TA311111 at a dilution of 1/100.

 

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