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Home Antibody All anti-ZBTB5 antibodies

Anti-ZBTB5 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319801
  • Rabbit Polyclonal ZBTB5 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC414902) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenZBTB5 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ZBTB6.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferZBTB5 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification ZBTB5 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens zinc finger and BTB domain containing 5 (ZBTB5)
Alternative NameOTTHUMP00000021384; OTTHUMP00000046108; zinc finger and BTB domain containing 5
Database LinkNP_055687
FunctionZBTB5 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21. ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter. ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of ZBTB5 in mouse brain tissue lysate with ZBTB5 antibody at (A) 1 and (B) 2 ug/mL.
IHC Image
Immunohistochemistry of ZBTB5 in human brain tissue with ZBTB5 antibody at 2.5 ug/mL.
IF Image
Immunofluorescence of ZBTB5 in human brain tissue with ZBTB5 antibody at 20 ug/mL.

 

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