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Anti-YWHAG Antibody KC21
Also for YWHAG (NM_012479)
|This antibody was raised against an N-terminal fragment of human 14-3-3 gamma where the N-terminal Val was acetylated.|
||Lot dependent; please refer to CoA along with shipment
|Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma (YWHAG)|
Entrez Gene 7532 Human
|14-3-3 proteins are present as multigene families in most organisms. Signal-induced phosphorylation has the ability to change protein function. Sometimes, however, phosphorylation is not enough to change a protein's function. 14-3-3 proteins play an important role of bringing signal transduction to completion. They regulate many cellular processes that are important in cancer biology, such as apoptosis and cell-cycle checkpoints. |
|Druggable Genome Cell cycleOocyte meiosisNeurotrophin signaling pathway|
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14-3-3 gamma detected in lysates. Lane 1: HeLa cell lysates, Lanes 2 and 3: bengamide treated lysates (8h and 24h, respectively).
Immunocytochemistry/Immunofluorescence: 14-3-3 gamma [ac Val2] antibody was tested in SH-SY5Y cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).