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Home Antibody All anti-XRCC5 antibodies
UltraMAB

Anti-XRCC5 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590469
  • Rabbit Polyclonal Ku80 Antibody
100ug 325 In Stock
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WB(2)
IHC(9)
ELISA(1)

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the C Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman , Dog , Monkey , Mouse Concentration1.01mg/ml
Guaranteed Application *WB, ELISA, IHC Suggested Dilutions WB 1:5000~20000, IHC 1:150,ELISA 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (XRCC5)
Alternative NameKARP-1; KARP1; KU80; Ku86; KUB2; NFIV
Database LinkNP_066964
FunctionOriginally identified as an autoantigen, the Ku protein are nuclear proteins found in eukaryotes. They exist as a heterodimer consisiting of Ku 70 and Ku 80, migrating at approximately 70 and 80 kDa respectively. They bind to DNA ends at double strand breaks. The Ku proteins interact with the DNA-dependent protein kinase (DNA-PK) and participate in the targeting of DNA-PK to DNA. The Ku proteins may participate in numerous cellular processes, including DNA repair and replication, cell signalling, cell proliferation, transcriptional activation and apoptosis.
Related Pathway

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY XRCC5 (RC210649, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-XRCC5.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-XRCC5 polyclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
ELISA Image
ELISA: Ku80 Antibody
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-XRCC5 rabbit polyclonal antibody. (TA590469)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-XRCC5 rabbit polyclonal antibody. (TA590469)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-XRCC5 rabbit polyclonal antibody. (TA590469)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-XRCC5 rabbit polyclonal antibody. (TA590469)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-XRCC5 rabbit polyclonal antibody. (TA590469)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-XRCC5 rabbit polyclonal antibody. (TA590469)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-XRCC5 rabbit polyclonal antibody. (TA590469)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-XRCC5 rabbit polyclonal antibody. (TA590469)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-XRCC5 rabbit polyclonal antibody. (TA590469)

 

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