Anti-XRCC1 TrueMAB Antibody clone 2E8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

SKU	Description	Amount	Price	Availability*
TA500881	anti-XRCC1 mouse monoclonal antibody, clone 2E8 FREE positive control: HEK293T cell transient overexpression lysate (LC401897) , 20ug	100ul	$325	In Stock
CF500881	Carrier-free (BSA/glycerol-free) XRCC1 mouse monoclonal antibody, clone 2E8	100ug	$450	3-4 weeks
TA802519S	Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9	30ul	$100 $50*	In Stock

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

Also for XRCC1 (NM_006297)

OriGene Data

Immunogen	Full length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.
Clone Name	clone 2E8	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IF	Suggested Dilutions	WB 1:2000, IF 1:100,
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1)
Alternative Name	RCC
Database Link	NP_006288
Function	The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq].
Related Pathway

* Shipping is in business days

* OriGene provides validated application data and protocol, with money back guarantee.

WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY XRCC1 (RC204952, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-XRCC1.

IF Image

Anti-XRCC1 mouse monoclonal antibody (TA500881) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY XRCC1(RC204952).

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

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