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Anti-WT1 Antibody 6F-H2


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  • Mouse Monoclonal Antibody against Wilms Tumor 1 (6F-H2)
100ul 325 In Stock
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OriGene Data

ImmunogenHuman recombinant WT1 protein (residues 1-181). [Swiss-Prot# P19544]
Clone Name6F-H2 IsotypeIgG1 kappa
Species Reactivityhuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 2 ug/ml
BufferTris-glycine, 150mM NaCl and 0.05% sodium azide
Purification IgG purified

Reference Data

Target NameHomo sapiens Wilms tumor 1 (WT1), transcript variant D
Alternative NameAWT1; EWS-WT1; GUD; NPHS4; WAGR; WIT-2; WT33
Database LinkNP_077744
Entrez Gene 7490 Human
FunctionWilms?tumor (WT) is an embryonal malignancy of the kidney that affects 1 in 10,000 infants and, like retinoblastoma, is observed in both sporadic and inherited forms. The Wilms?tumor locus has been mapped at chromosome 11p13 as a tumor suppressor gene which encodes a DNA binding protein with four zinc fingers and a glutamine-proline rich amino terminus. The Wilms?tumor protein binds the DNA sequence GCGGGGGCG, a recognition element common to the early growth response (Egr) family of Zn2+ finger transcriptional activators. However, in contrast to Egr transcription factors, WT1 behaves as a transcriptional repressor in transient transfection assays with synthetic promotor constructs.
Related PathwayTranscription FactorsDruggable Genome

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western Blot- Wilms Tumor 1 Antibody (6F-H2) detects WT1 in 293 cell lysate
IHC Image
Immunohistochemistry- IHC analysis of Wilms Tumor 1 in human renal cancer using DAB with hematoxylin counterstain.


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