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Home Antibody All anti-WNT4 antibodies

Anti-WNT4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302700
  • Goat Polyclonal Antibody against WNT4
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403075) , 20ug
100ug 325 In Stock
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WB(1)

OriGene Data

Immunogen Peptide with sequence C-SNWLYLAKLSSVGS, from the internal region of the protein sequence according to NP_110388.2.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Mouse, Rat Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-3.0ug/ml
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens wingless-type MMTV integration site family, member 4 (WNT4)
Alternative NameSERKAL; WNT-4
Database LinkNP_110388
FunctionThe WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq].
Related Pathway
Hedgehog signaling pathway
Melanogenesis
Wnt Signaling Pathway

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WB Image
TA302700 (1ug/ml) staining of JURKAT lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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