Home Antibody All anti-WFS1 antibodies
Also for WFS1 (NM_006005)
|A 110 amino acid region of the N-terminal region of the human protein|
|human, rat, mouse
||Lot dependent; please refer to CoA along with shipment
|Homo sapiens Wolfram syndrome 1 (wolframin) (WFS1), transcript variant 1|
|CTRCT41; WFRS; WFS; WFSL|
Entrez Gene 7466 Human
Entrez Gene 22393 Mouse
Entrez Gene 83725 Rat
|WFS1 is a novel component of Wolfram syndrome, a rare form of juvenile diabetes. WFS1 plays an important role in maintaining homeostasis of the endoplasmic reticulum (ER) in the pancreas. It is normally up-regulated during insulin secretion, whereas inactivation of the protein can cause ER stress. Chronic ER stress is a major involvement in Wolfram syndrome.|
|TransmembraneDruggable Genome |
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Western Blot: WFS1 Antibody TA301684 - Analysis of WFS1 in insulinoma cells.
Detection of WFS1 in insulinoma cells