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Home Antibody All anti-WAC antibodies

Anti-WAC Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319920
  • Rabbit Polyclonal WAC Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC413880) , 20ug
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenWAC antibody was raised against a 19 amino acid peptide near the center of human WAC .
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsELISA, WB: 1 ug/ml, IHC, IF
BufferWAC Antibody is supplied in PBS containing 0.02% sodium azide.
Purification WAC Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens WW domain containing adaptor with coiled-coil (WAC), transcript variant 1
Alternative NameBM-016; PRO1741; Wwp4
Database LinkNP_057712
FunctionWAC Antibody: The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35. Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination. WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites. WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress.
Related Pathway

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WB Image
Western blot analysis of WAC in human testis tissue lysate with WAC antibody at 1 ug/mL.

 

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