Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor (VDR), transcript variant 1
Synonyms:
NR1I1
Immunogen
A synthetic peptide corresponding to residues in human Vitamin D3 Receptor was used as an immunogen.
Buffer
Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Vitamin D3 Receptor is the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. It belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism, though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in Vitamin D3 Receptor are associated with type II vitamin D-resistant rickets.
Related Pathway
TGF Beta Signaling Pathway
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