Home Antibody All anti-USP11 antibodies
Anti-USP11 Antibody EPR4346
Also for USP11 (NM_004651)
|A synthetic peptide corresponding to residues in human USP11 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IHC-P.
|Homo sapiens ubiquitin specific peptidase 11 (USP11)|
Entrez Gene 8237 Human
Entrez Gene 236733 Mouse
Entrez Gene 408217 Rat
|USP11 (ubiquitin-specific protease 11) is a member of a protein family that cleaves polyubiquitin chains and/or ubiquitin precursors (1). USP11 possesses Cys box, His box, Asp and KRF domains, which are highly conserved in many ubiquitin-specific proteases (2). Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates (3).|
|ProteaseDruggable Genome |
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Western blot - USP11 antibody [EPR4346]; All lanes : Anti-USP11 antibody [EPR4346] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : Human testis cell lysate.Lane 4 : Huma fetal kidney cell lysate.Lane 5 : LnCaP cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 110 kDa.Observed band size : 110 kDa.
Immunocytochemistry/ Immunofluorescence - USP11 antibody [EPR4346]; Immunofluorescent staining of USP11 in HeLa cells, using TA307273 at a dilution of 1/100.