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Home Antibody All anti-USP11 antibodies

Anti-USP11 Antibody EPR4346

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307273
  • Rabbit monoclonal antibody against USP11(clone EPR4346)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417844) , 20ug
100ul $325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human USP11 was used as an immunogen.
Clone NameEPR4346 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens ubiquitin specific peptidase 11 (USP11)
Alternative NameUHX1
Database LinkNP_004642
FunctionUSP11 (ubiquitin-specific protease 11) is a member of a protein family that cleaves polyubiquitin chains and/or ubiquitin precursors (1). USP11 possesses Cys box, His box, Asp and KRF domains, which are highly conserved in many ubiquitin-specific proteases (2). Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates (3).
Related Pathway

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WB Image
Western blot - USP11 antibody [EPR4346]; All lanes : Anti-USP11 antibody [EPR4346] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : Human testis cell lysate.Lane 4 : Huma fetal kidney cell lysate.Lane 5 : LnCaP cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 110 kDa.Observed band size : 110 kDa.
IF Image
Immunocytochemistry/ Immunofluorescence - USP11 antibody [EPR4346]; Immunofluorescent staining of USP11 in HeLa cells, using TA307273 at a dilution of 1/100.

 

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