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Anti-USP11 Antibody EPR4346


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against USP11(clone EPR4346)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417844) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human USP11 was used as an immunogen.
Clone NameEPR4346 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 110 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens ubiquitin specific peptidase 11 (USP11)
Alternative NameUHX1
Database LinkNP_004642
Entrez Gene 8237 Human
Entrez Gene 236733 Mouse
Entrez Gene 408217 Rat
FunctionUSP11 (ubiquitin-specific protease 11) is a member of a protein family that cleaves polyubiquitin chains and/or ubiquitin precursors (1). USP11 possesses Cys box, His box, Asp and KRF domains, which are highly conserved in many ubiquitin-specific proteases (2). Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates (3).
Related PathwayProteaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - USP11 antibody [EPR4346]; All lanes : Anti-USP11 antibody [EPR4346] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : Human testis cell lysate.Lane 4 : Huma fetal kidney cell lysate.Lane 5 : LnCaP cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 110 kDa.Observed band size : 110 kDa.
Immunocytochemistry/ Immunofluorescence - USP11 antibody [EPR4346]; Immunofluorescent staining of USP11 in HeLa cells, using TA307273 at a dilution of 1/100.


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