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Anti-USH1C Antibody EPR8131


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against USH1C
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human USH1C was used as an immunogen.
Clone NameEPR8131 IsotypeIgG
Species ReactivityMouse, Rat, Human, Spermophilus tridecemlineatus ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100
Predicted MW Explanation 62 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens Usher syndrome 1C (autosomal recessive, severe) (USH1C), transcript variant 1
Alternative NameAIE-75; DFNB18; DFNB18A; NY-CO-37; NY-CO-38; PDZ-45; PDZ-73; PDZ-73/NY-CO-38; PDZ73; PDZD7C;
Database LinkNP_005700
Entrez Gene 10083 Human
Entrez Gene 72088 Mouse
Entrez Gene 308596 Rat
FunctionUSH1C is a scaffold protein that functions in the assembly of Usher protein complexes. It contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in USH1C are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18 (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-USH1C antibody [EPR8131]; All lanes : Anti-USH1C antibody [EPR8131] at 1/10000 dilution.Lane 1 : Human fetal kidney lysate.Lane 2 : Human colon lysate.Lane 3 : Caco 2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 62 kDa.
Western blot - Anti-USH1C antibody [EPR8131]; All lanes : Anti-USH1C antibody [EPR8131] at 1/2500 dilution.Lane 1 : Squirrel cochlea.Lane 2 : Mouse cochlea.Lane 3 : Squirrel colon.Lane 4 : Mouse colon.Lane 5 : Caco2 cells.Secondary.HRP linked Goat anti-rabbit IgG polyclonal at 1/20000 dilution.developed using the ECL technique.Performed under reducing conditions.Predicted band size : 62 kDa.Additional bands at : 40 kDa (possible isoform),67 kDa (possible isoform).Exposure time : 30 seconds
Other-Anti-USH1C antibody [EPR8131](TA310931); Equilibrium disassociation constant (KD)..


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