Anti-UNG Antibody, EPR4371

Also for UNG (NM_080911)

Gene Name	Homo sapiens uracil-DNA glycosylase (UNG), transcript variant 2
Synonyms:	DGU; HIGM4; HIGM5; UDG; UNG1; UNG15; UNG2
Immunogen	A synthetic peptide corresponding to residues in human UNG was used as an immunogen.
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Clone Name	EPR4371	Isotype	Rabbit IgG
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IHC	Suggested Dilutions	FC: 1:10 - 100, ICC: 1:100 - 250, IHC: 1:250 - 1:500, WB: 1:1,000 - 10,000,
Background	UNG functions to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues (1).
Related Pathway

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WB Image

Western blot analysis on (A) HeLa, (B) mouse muscle, (C) rat muscle, and (D) human skeletal muscle lysates using anti-UNG RabMAb .

IHC Image

Immunohistochemical analysis of paraffin-embedded human muscle tissue using anti-UNG RabMAb .

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Anti-UNG Antibody EPR4371

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